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Steven H Graham Selected Research

butyloxycarbonyl- O- methyl- aspartyl- fluoromethyl ketone

2/2007boc-Aspartyl(OMe)-fluoromethylketone attenuates mitochondrial release of cytochrome c and delays brain tissue loss after traumatic brain injury in rats.

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Steven H Graham Research Topics

Disease

20Ischemia
03/2017 - 01/2002
18Traumatic Brain Injuries (Traumatic Brain Injury)
11/2021 - 05/2002
15Brain Ischemia (Cerebral Ischemia)
12/2019 - 01/2002
11Brain Injuries (Brain Injury)
05/2015 - 01/2002
9Stroke (Strokes)
01/2019 - 07/2004
9Hypoxia (Hypoxemia)
05/2015 - 12/2004
7Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
12/2019 - 12/2004
6Infarction (Infarctions)
12/2019 - 06/2005
4Heart Arrest (Cardiac Arrest)
06/2013 - 02/2003
3Neurodegenerative Diseases (Neurodegenerative Disease)
01/2019 - 02/2011
3Ischemic Stroke
01/2014 - 12/2006
3Infections
05/2010 - 03/2004
3Parkinson Disease (Parkinson's Disease)
04/2010 - 09/2004
2Inflammation (Inflammations)
04/2016 - 01/2014
2Cerebral Infarction
04/2006 - 07/2002
2Central Nervous System Diseases (CNS Diseases)
09/2004 - 04/2003
2Transient Ischemic Attack
10/2003 - 05/2002
2Craniocerebral Trauma (Head Injury)
07/2003 - 02/2003
2Brain Contusion
07/2002 - 05/2002
1Coma (Comas)
11/2020
1Alzheimer Disease (Alzheimer's Disease)
01/2019
1Dementia (Dementias)
01/2019
1Parkinsonian Disorders (Parkinsonism)
01/2019
1Chronic Traumatic Encephalopathy
01/2019
1Spinal Cord Injuries (Spinal Cord Injury)
04/2016
1Cerebrovascular Disorders (Cerebrovascular Occlusion)
01/2014
1Neuroinflammatory Diseases
01/2014
1Mitochondrial Diseases (Mitochondrial Disease)
09/2009
1Cognitive Dysfunction
07/2008
1Starvation
03/2008

Drug/Important Bio-Agent (IBA)

18Proteins (Proteins, Gene)FDA Link
11/2021 - 04/2002
10Cyclooxygenase 2 (Cyclooxygenase-2)IBA
05/2015 - 04/2003
8CaspasesIBA
05/2015 - 04/2002
7ProstaglandinsIBA
01/2014 - 09/2007
4UbiquitinIBA
11/2021 - 04/2010
4Neuroprotective AgentsIBA
04/2016 - 07/2002
4Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
01/2014 - 04/2003
4Glucose (Dextrose)FDA LinkGeneric
08/2007 - 05/2002
4Caspase 3 (Caspase-3)IBA
06/2005 - 05/2002
3Ubiquitin Thiolesterase (Ubiquitin Carboxy-Terminal Hydrolase)IBA
11/2021 - 02/2011
3Proteasome Endopeptidase Complex (Proteasome)IBA
11/2021 - 01/2017
3LipidsIBA
11/2021 - 03/2017
3salicylhydroxamic acid (SHAM)IBA
01/2019 - 04/2002
3Oxygen (Dioxygen)IBA
01/2014 - 10/2003
3cyclopentenoneIBA
08/2013 - 04/2010
3Cytochromes c (Cytochrome c)IBA
12/2012 - 06/2005
31- ((4- methylsulfonyl)phenyl)- 3- trifluoromethyl- 5- (4- fluorophenyl)pyrazoleIBA
09/2007 - 12/2004
3Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
09/2007 - 12/2004
3Glutamic Acid (Glutamate)FDA Link
08/2007 - 05/2002
2Biomarkers (Surrogate Marker)IBA
11/2020 - 12/2012
2Pharmaceutical PreparationsIBA
11/2020 - 01/2014
2Rosiglitazone (Avandia)FDA Link
04/2016 - 04/2006
2Ubiquitinated ProteinsIBA
08/2013 - 02/2011
2EnzymesIBA
06/2013 - 05/2010
2HSP27 Heat-Shock ProteinsIBA
02/2012 - 12/2008
2Phosphotransferases (Kinase)IBA
09/2009 - 12/2008
2Heat-Shock Proteins (Heat-Shock Protein)IBA
12/2008 - 02/2003
2HET0016IBA
11/2008 - 12/2006
220-hydroxy-5,8,11,14-eicosatetraenoic acidIBA
11/2008 - 12/2006
2Reactive Oxygen Species (Oxygen Radicals)IBA
03/2008 - 09/2007
2Dinoprostone (PGE2)FDA Link
03/2008 - 07/2005
2AntioxidantsIBA
03/2008 - 05/2002
2Nerve Growth Factor (NGF)IBA
02/2007 - 03/2004
2Caspase 9IBA
06/2005 - 05/2002
2Apoptosis Inducing FactorIBA
10/2003 - 07/2002
2Messenger RNA (mRNA)IBA
05/2003 - 04/2002
2Dialysis SolutionsIBA
07/2002 - 05/2002
2Excitatory Amino AcidsIBA
07/2002 - 05/2002
1Nicotinamide PhosphoribosyltransferaseIBA
12/2019
1Amyloid beta-PeptidesIBA
01/2019
1tau Proteins (tau Protein)IBA
01/2019
1SynucleinsIBA
01/2019
1Peptides (Polypeptides)IBA
01/2019
1Cysteine (L-Cysteine)FDA Link
01/2019
1Protein AggregatesIBA
03/2017
1Therapeutic UsesIBA
01/2017
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
04/2016
1Protein Disulfide-IsomerasesIBA
05/2015
1EicosanoidsIBA
01/2014
1Arachidonic Acid (Vitamin F)IBA
01/2014
1Oxidants (Oxidizing Agents)IBA
01/2014
1Inflammation MediatorsIBA
01/2014
1Benzoic Acid (Potassium Benzoate)FDA Link
12/2013
1Epoxide HydrolasesIBA
12/2013
1AcidsIBA
12/2013
1prostaglandin R2 D-isomerase (prostaglandin D2 synthase)IBA
12/2013
14- (4- (3- adamantan- 1- ylureido)cyclohexyloxy)benzoic acidIBA
12/2013
1triphenyltetrazoliumIBA
12/2013
1LipocalinsIBA
12/2013
1Culture MediaIBA
12/2012
1MAP Kinase Kinase Kinase 5IBA
02/2012
1Deubiquitinating EnzymesIBA
02/2011
1Peroxidase (Myeloperoxidase)IBA
05/2010
1HydrolasesIBA
04/2010
1valdecoxib (Bextra)FDA Link
07/2009
1bcl-2-Associated X Protein (bcl 2 Associated X Protein)IBA
07/2008
1Prostaglandin D2IBA
03/2008
1EstersIBA
03/2008

Therapy/Procedure

4Therapeutics
11/2020 - 09/2004
2Resuscitation
06/2013 - 12/2012